Fine Lines
Crow's feet, forehead, and perioral lines softened
PRP Facials in Big Pine Key, FL: Collagen-Boosting Skin Rejuvenation with Your Own Plasma
Microneedling with platelet-rich plasma that boosts collagen, smooths texture, and revives your skin's natural glow
Session Length:60-90 minutes
Series:3 sessions over 3 months
Initial Glow:1-2 weeks
Peak Collagen Results:3-6 months
Downtime:24-72 hours redness
Performed By:Dr. Gregory Keifer, D.O.
Skin Renewal
From Sun-Weathered to Restored Glow
The Problem and the Solution
Living in the Florida Keys is a gift, but the sun is unforgiving. Years on the water leave sun spots, uneven tone, fine lines around the eyes and skin that no longer bounces back. Most OTC skincare promises rejuvenation but can't reach the dermis where collagen is built. Peels and generic facials produce short-lived results with little structural change.
PRP facials at Florida Keys Primary Care & Wellness deliver your own concentrated platelets into the dermis through fine microneedling channels. The growth factors trigger fibroblasts to produce new collagen and elastin, the structural proteins that give skin its tone and firmness. Performed by Dr. Keifer in a sterile clinical setting, this is a true medical procedure rather than a casual spa offering, and the long-term skin quality changes show it.
Treatment Timeline
Treatment Time
60-90 minutes per session
Series
3 sessions over 3 months
Initial Glow
1-2 weeks post-treatment
Peak Results
3-6 months as collagen rebuilds
Recovery
24-72 hours mild redness
What Is a PRP Facial?
Autologous Collagen Induction
A PRP facial is a two-part regenerative skin treatment. First, microneedling creates thousands of micro-channels in the skin to trigger the natural wound-healing cascade. Then, platelet-rich plasma drawn from your own blood is applied topically and pressed into the channels, delivering concentrated growth factors directly into the dermis.
The science centers on collagen induction. Growth factors such as PDGF, TGF-beta, and VEGF signal fibroblasts to produce new collagen and elastin over the following weeks and months. The result is firmer skin, improved texture, smaller pores, reduced fine lines, and a more even tone. Because PRP is autologous, there are no foreign substances introduced and no risk of rejection.
Many patients pair PRP facials with laser skin resurfacing with ADVATx or maintain results with medical-grade skincare. Clinical research is summarized in studies indexed by PubMed.
Benefits of PRP Facials
Natural Skin Renewal
2000+ Satisfied patients
- 01
100% Autologous
Treatment is built from your own blood with no synthetic additives
- 02
Real Collagen Building
Stimulates fibroblasts to produce new collagen and elastin
- 03
Minimal Downtime
Most patients are presentable within 1-2 days
- 04
Physician Supervised
Performed by Dr. Keifer in a clinical setting
- 05
Pairs With Laser
Stacks well with ADVATx laser for compounding results
- 06
Whole-Face Improvement
Benefits tone, texture, fine lines, and firmness in one treatment
PRP Facial vs Microneedling vs Chemical Peel
Treatment Options
| Treatment | Mechanism | Time | Results | Duration | Downtime | Best For |
|---|---|---|---|---|---|---|
| PRP Facial | Microneedling plus autologous growth factors stimulate collagen | 60-90 min | Glow at 1-2 weeks; collagen at 3-6 months | 12-18 months with maintenance | 24-72 hours | Texture, firmness, fine lines, sun damage |
| Microneedling Alone | Controlled micro-injury triggers wound healing | 30-60 min | Subtle texture improvement at 4-6 weeks | 6-12 months | 24-48 hours | Mild texture and tone changes |
| Chemical Peel | Acid solution exfoliates upper skin layers | 30-45 min | Brightening at 1-2 weeks | Variable by depth | 3-7 days (medium peel) | Pigmentation and surface concerns |
Who Is a Good Candidate for a PRP Facial?
Best Outcomes
PRP facials are well suited for adults seeking to address sun damage, fine lines, uneven tone, and texture without surgery, fillers, or aggressive lasers. Dr. Keifer will assess your skin and medical history during the consultation to confirm you are a candidate.
Ideal Candidates for PRP Facials
- Adults with photoaged skin from years of Keys sun exposure
- Patients seeking natural collagen-driven rejuvenation
- Those with acne scarring, mild laxity, or dull texture
- Anyone wanting to combine PRP with ADVATx laser resurfacing
- Patients in good general health with realistic expectations
Who Should Wait or Avoid PRP Facials
- Active facial infections, open wounds, or severe inflammatory acne
- Bleeding disorders, low platelet counts, or anticoagulant therapy that cannot be paused
- History of poor wound healing or keloid scarring
- Pregnancy or breastfeeding (out of caution; safety data is limited)
- Recent isotretinoin use within the last 6 months
If your goals also include addressing uneven skin tone and sun damage or fine lines and facial aging, we can build a layered plan during your visit.
Your PRP Facial Visit
What to expect during your PRP facial, from blood draw and processing to gentle application and aftercare
Consultation
Dr. Keifer reviews your skin, history, and goals to confirm PRP facial candidacy.
Blood Draw
Our Medical Assistants draw 30-60 mL of blood using sterile venipuncture technique.
Centrifugation
Your sample is processed in a clinical-grade centrifuge for 8-10 minutes to isolate PRP.
Skin Prep & Numbing
Face is cleansed, then topical numbing cream is applied for 20-30 minutes.
Microneedling + PRP
Dr. Keifer performs microneedling and applies PRP into the channels for collagen stimulation.
Side Effects and Safety
Common skin reactions, less typical effects, and rare risks to know before each PRP facial session
-
Common, Expected PRP Facial Side Effects
Because PRP is autologous, allergic reactions are essentially nonexistent. Most patients leave with mild redness, light swelling, and a slightly flushed look that fades within 24 to 48 hours. Pinpoint marks, brief tenderness, and temporary skin sensitivity are also normal. -
Less Common Side Effects After Treatment
Some patients experience small bruises, crusting on microneedled areas, or short-lived skin tightness for a few days. Slight breakouts can occur as the skin clears and renews. These resolve quickly with gentle skincare, hydration, and consistent daily SPF use. -
Rare Risks and How We Help You Avoid Them
Infection, scarring, or persistent reactions are rare when PRP facials are performed using sterile technique by trained physicians. We screen for skin infections, blood disorders, and recent treatments before each session. Needling depth keeps treatment safe.
Cost of PRP Facials in Big Pine Key
Transparent, Physician-Led Pricing
PRP facials are priced per session, with most patients investing in a series of three treatments spaced four to six weeks apart for optimal collagen results. Annual maintenance sessions are recommended to preserve your investment.
We offer financing through Cherry and CareCredit for patients across Big Pine Key, Marathon, Sugarloaf Key, and Key West. Bundle pricing is available for patients pairing PRP facials with ADVATx laser resurfacing or with PRP hair restoration.
For long-term skin health, we recommend daily SPF and a personalized regimen using medical-grade skincare from our clinic. Explore our full regenerative medicine menu to plan a layered approach.
Why Choose Florida Keys Primary Care
Natural skin rejuvenation using your own platelets, performed in a sterile, physician-led clinical setting
Sterile Clinical Protocol
Every PRP draw and microneedling pass is sterile and physician-supervised
Physician-Led Care
Dr. Keifer performs each PRP facial start to finish
Continuity With Primary Care
Your skin care plan is informed by full medical history and labs
Clinical-Grade Equipment
Medical centrifuge and FDA-cleared microneedling devices
Uses Your Own Biology
Natural rejuvenation drawn from your own blood, not synthetic fillers
Minimal Downtime
Most patients return to daily routines the very next day
Related Services
Pair PRP facials with these complementary treatments at our Big Pine Key clinic.
Medical and Preventive Care
Annual physicals, chronic disease management, walk-in sick visits and in-office procedures — physician-led care for the Middle and Lower Keys
Learn More
Wellness Treatments
Hormone Replacement, Medical Weight Loss, TMS Therapy, Emsella, Emsculpt Neo and more — physician-led wellness for the Lower Keys
Learn More
Regenerative Treatments
Hair restoration, PRP facials and PRP joint injections — physician-led regenerative medicine for the Lower Keys
Learn More
Aesthetic Treatments
Botox, dermal fillers, ADVATx laser resurfacing, Emface, Denza, Nirvana laser hair removal and physician-curated skincare — all under one roof
Learn MorePRP Facial FAQ
Common Patient Questions
What is a PRP facial?
A PRP facial combines microneedling with platelet-rich plasma drawn from your own blood. The growth factors are pressed into the skin to stimulate collagen and renewal in a way over-the-counter products cannot.
How much is a PRP facial in Big Pine Key?
Pricing varies by session count and whether the treatment is bundled with laser or skincare. Most patients invest in a series of three sessions, and we offer Cherry and CareCredit financing.
Does a PRP facial actually work?
Yes. Peer-reviewed studies show PRP combined with microneedling improves skin texture, firmness, and tone by stimulating collagen and elastin production over 3-6 months.
What is the downtime after a PRP facial?
Most patients experience 24-72 hours of redness and mild sensitivity, similar to a light sunburn. Makeup can typically be reapplied at 24 hours and normal activity resumes the same day.
When will I see results from my PRP facial?
An initial glow appears within 1-2 weeks. Real collagen-driven changes (firmness, texture, fine line softening) build progressively over 3-6 months as new collagen forms.
Can I do PRP and laser together?
Yes. PRP pairs very well with ADVATx laser resurfacing and can shorten recovery while compounding results. Dr. Keifer will recommend timing during consultation.
What are the side effects of a PRP facial?
Most patients experience mild redness, swelling, and sensitivity for 24-72 hours. Because PRP is your own blood, there is essentially no risk of allergic reaction.
Schedule Your PRP Facials Consultation
References
- PubMed (PMID: 30889637) - Clinical evidence supports PRP for facial rejuvenation, demonstrating improvements in skin texture, firmness, and elasticity.
- PubMed (PMID: 31021077) - Randomized study confirms PRP combined with microneedling produces superior outcomes for photoaged skin compared to microneedling alone.
- PubMed (PMID: 30471810) - Review of PRP preparation and clinical applications confirms safety and efficacy of autologous growth factors for skin regeneration. See PubMed.