Annual physical exam at Florida Keys Primary Care in Big Pine Key, FL

Medical and Preventive Care in Big Pine Key, FL: Your First Line of Defense for Lasting Health

Annual physicals, chronic disease management, walk-in sick visits and in-office procedures — physician-led care for the Middle and Lower Keys

Dr. Gregory Keifer reviewing patient chart at Florida Keys Primary Care in Big Pine Key, FL
Comprehensive Care, Close to Home

Forty Years of Trusted Medical Care in the Lower Keys

Formerly Big Pine Medical, now Florida Keys Primary Care & Wellness

Medical and preventive care in Big Pine Key, FL is the foundation of Florida Keys Primary Care & Wellness. For four decades — first as Big Pine Medical, now as Florida Keys Primary Care — we've cared for residents and visitors from Marathon to Key West, pairing physician-led medicine with technology that used to require a drive to Miami.

Our team is led by Dr. Gregory Keifer, D.O., a Florida-licensed osteopathic physician focused on preventive health, alongside Tabble Memoli, MSN, APRN, in family practice since 2012. Together they handle the full primary-care picture: annual physicals, chronic disease management (diabetes, high blood pressure and more), in-office procedures, age-appropriate preventive screenings, and same-day sick visits.

What sets a primary care home apart is continuity. The same team, year after year, building on every visit — that's how a rural Keys practice stays trusted for forty years.

Our Medical & Preventive Care Services

Five Core Services for the Middle and Lower Keys

From your yearly physical to same-day sick visits and minor surgical procedures

Annual Physical Exams

Comprehensive yearly wellness visits with full lab work, age-appropriate cancer screenings and a personalized care plan.

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Chronic Disease Management

Ongoing care for diabetes, high blood pressure, high cholesterol, thyroid disorders and heart disease — coordinated by your primary physician.

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In-Office Procedures

Skin lesion removal, joint injections, biopsies, abscess drainage and laceration repair — minor surgical care without the hospital.

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Preventive Care and Health Screenings

Thyroid panels, cholesterol testing, diabetes screenings, cancer screenings and full preventive lab work tied to your age and history.

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Walk-In Doctor and Sick Visits

Same-day appointments for acute illness, minor injuries, infections and after-hours concerns — no emergency room necessary.

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Patient consultation at Florida Keys Primary Care in Big Pine Key, FL
How We Compare

Which Medical Service Is Right for You?

A simple guide to help you choose the right type of visit

You should book an annual physical or preventive screening if:

  • You are due for your yearly wellness visit, even if you feel fine
  • You have not had recent labs (cholesterol, A1C, thyroid)
  • You have a family history of heart disease, diabetes or cancer
  • You are turning a screening age (40, 45, 50, 65)
  • You are establishing care with a new primary physician

You should book chronic disease management if:

  • You already have a diagnosis of diabetes, hypertension, high cholesterol, thyroid disease or heart disease
  • You take a daily medication that needs ongoing review
  • You want to lower your numbers without simply adding more medication

You should book an in-office procedure visit if:

  • You have a skin lesion, mole or suspicious spot that needs to be removed or biopsied
  • You have joint pain that may benefit from a cortisone injection
  • You have an abscess or boil that needs drainage
  • You have a small laceration that may need stitches

You should use the walk-in doctor for:

  • Sudden cough, sore throat, fever or sinus infection
  • UTI symptoms, ear pain, pink eye
  • Minor cuts, sprains, falls or burns
  • Anything you would normally take to urgent care
Florida Keys Primary Care and Wellness office reception in Big Pine Key, FL
Why Choose Us

Why Choose Florida Keys Primary Care for Medical Care in Big Pine Key, FL

Forty years of community medicine, the same team, the modern technology you would otherwise drive for

Choosing a primary care practice in the Lower Keys is choosing how you'll be cared for over the next decade. Patients stay with us for three reasons. Continuity: Dr. Keifer, Tabble Memoli and our team know you, track your numbers year over year, and catch small changes early. Convenience: most issues that would mean an ER trip or a drive to Miami are handled right here in our renovated Big Pine Key office. Scope: we're one of the few rural Keys practices combining traditional primary care with the modern wellness, hormone, weight loss and aesthetic technology Keys patients are increasingly asking for.

No being passed between three specialists for a single problem. No rushed 7-minute appointments. Just a physician-led team practicing osteopathic, whole-person medicine since 2012 and earlier.

We accept most major insurances including Medicare. Cherry and Care Credit financing is available for wellness and aesthetic services outside insurance.

Patient receiving blood pressure check at Florida Keys Primary Care in Big Pine Key, FL
Conditions We Manage

Common Health Concerns We Treat at Our Big Pine Key Office

Cross-link to concern pages for deeper information

Many patients arrive knowing what's wrong but not which service they need. Below are the most common concerns we manage — click through for how we treat each one.

Frequently Asked Questions

FAQ About Medical and Preventive Care at Florida Keys Primary Care

Do you accept Medicare?

Yes. Florida Keys Primary Care & Wellness accepts Medicare and most major insurance plans for our medical and preventive care services. Wellness, hormone and aesthetic services that fall outside insurance coverage can be financed through Cherry or Care Credit. Call (305) 872-3321 to verify your specific plan.

Do you treat all ages?

We see patients ages 2 and older. Our primary care patient base leans Medicare-aged, but we welcome adults and families across the Lower and Middle Keys. Pediatric patients under 2 are referred to a pediatrician.

Do I need a referral to schedule an appointment?

No referral is needed to establish care or to book any of our medical, wellness or aesthetic services. You can call (305) 872-3321 or book a free consultation directly.

Do you offer same-day appointments for sick visits?

Yes. Our walk-in doctor service handles same-day sick visits and minor injury care during business hours. Call ahead at (305) 872-3321 to confirm availability — most days we can see you the same day without an appointment.

Are you the same practice as Big Pine Medical?

Yes. Florida Keys Primary Care & Wellness is the same practice — same physicians, same location at 29980 Overseas Hwy — that the community has known as Big Pine Medical for 40 years. The name updated to reflect the expanded scope of wellness and aesthetic services we now offer.

What insurance plans do you accept?

We accept Medicare and most major commercial insurances for primary care. The simplest way to confirm coverage for your specific plan is to call our office at (305) 872-3321 before your visit.

Florida Keys Primary Care and Wellness office exterior in Big Pine Key, FL
Book Your Visit

Schedule Your Medical or Preventive Care Visit Today

Whether you are coming in for your annual physical, managing a chronic condition or just have something that needs to be looked at today, we are here. Call (305) 872-3321, email office@flkeyswellness.com, or book a free consultation online. Florida Keys Primary Care & Wellness is located at 29980 Overseas Hwy, Big Pine Key, FL 33043 — easy to reach from Marathon, Summerland Key, Cudjoe Key, Sugarloaf Key and the surrounding communities.